Brian Johnson, PhD
Assistant Professor
Pharmacology & Toxicology, Biomedical Engineering
Pharmacology & Toxicology, Biomedical Engineering
Colleges
Programs
Sections
- PHM 801 Fundamental Principles of Pharmacology and Toxicology (in-person) - Fall
- PHM 803 Chemical Disposition in Mammals (in-person) - Fall
- PHM 805 Receptor Pharmacology (in-person) - Fall
Education
- Postdoc, Biomedical Engineering, University of Wisconsin-Madison (2014-01-01—2020-04-30)
- PhD, Molecular and Environmental Toxicology, University of Wisconsin-Madison (2007-09-01—2013-12-22)
- BS, Biological Sciences, Michigan Technological University ()
Education
- QQQ 1Postdoc, 2Biomedical Engineering, 3University of Wisconsin-Madison 4Biomedical Engineering (2014-01-01—2020-04-30)
- QQQ 1PhD, 2Molecular and Environmental Toxicology, 3University of Wisconsin-Madison 4Molecular and Environmental Toxicology (2007-09-01—2013-12-22)
- QQQ 1BS, 2Biological Sciences, 3Michigan Technological University 4Biological Sciences ()
Funding
- Elucidating AHR signaling interplay in orofacial clefting and endocrine disruption using microplate microfluidics, National Institute of Environmental Health Sciences (2018-09-01—2020-08-31)
- Elucidating AHR signaling interplay in orofacial clefting and endocrine disruption using microplate microfluidics, National Institute of Environmental Health Sciences (2020-09-01—2023-08-31)
- Environmental, Microbial and Mammalian Biomolecular Responses to AhR Ligands, National Institute of Environmental Health Sciences (1988-12-07—2027-06-30)
Works
- Spatially dependent tissue distribution of thyroid hormones by plasma thyroid hormone binding proteins. Pflugers Archiv : European journal of physiology (2025)
- The Asymmetry Within: A Renewed Look at Cupids Bow in Unilateral Cleft Lip. The Journal of craniofacial surgery (2024-05-14)
- Crowdsourcing AOP development: Leveraging the thesis literature review to identify knowledge gaps and facilitate research translation. Current Research in Toxicology (2024)
- A minimal human physiologically based kinetic model of thyroid hormones and chemical disruption of plasma thyroid hormone binding proteins. Frontiers in endocrinology (2023-05-25)
- Fresh tissue procurement and preparation for multicompartment and multimodal analysis of the prostate tumor microenvironment. The Prostate (2022)
- A Microphysiological Approach to Evaluate Effectors of Intercellular Hedgehog Signaling in Development. Frontiers in cell and developmental biology (2021-02-09)
- A bioengineered organotypic prostate model for the study of tumor microenvironment-induced immune cell activation. Integrative biology : quantitative biosciences from nano to macro (2020-10-01)
- Engineered Perineural Vascular Plexus for Modeling Developmental Toxicity. Advanced healthcare materials (2020-07-01)
- Modeling chemical effects on breast cancer: the importance of the microenvironment in vitro. Integrative biology : quantitative biosciences from nano to macro (2020-03-01)
- Mri-based cancer lesion analysis with 3d printed patient specific prostate cutting guides. American journal of clinical and experimental urology (2019-08-15)
- Mammary adipose stromal cells derived from obese women reduce sensitivity to the aromatase inhibitor anastrazole in an organotypic breast model. FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2019-04-19)
- Evaluation of PEG-based hydrogel influence on estrogen receptor driven responses in MCF7 breast cancer cells. ACS biomaterials science & engineering (2019-01-01)
- Mammary fibroblasts reduce apoptosis and speed estrogen-induced hyperplasia in an organotypic MCF7-derived duct model. Scientific reports (2018-05-08)
- Vital ex vivo tissue labeling and pathology-guided micropunching to characterize cellular heterogeneity in the tissue microenvironment. BioTechniques (2018-01-01)
- Hepatic expression profiles in retroviral infection: relevance to drug hypersensitivity risk. Pharmacology research & perspectives (2017-04-26)
- Personalized in vitro cancer models to predict therapeutic response: Challenges and a framework for improvement. Pharmacology & therapeutics (2016-05-21)
- Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression. Clinical cancer research : an official journal of the American Association for Cancer Research (2016-02-04)
- Hepatocyte circadian clock controls acetaminophen bioactivation through NADPH-cytochrome P450 oxidoreductase. Proceedings of the National Academy of Sciences of the United States of America (2014-12-15)
- Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice. Proceedings of the National Academy of Sciences of the United States of America (2014-09-15)
- Aggregate culture of human embryonic stem cell-derived hepatocytes in suspension are an improved in vitro model for drug metabolism and toxicity testing. Toxicological sciences : an official journal of the Society of Toxicology (2014-04-20)
- An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells. Journal of immunology (Baltimore, Md. : 1950) (2010-08-18)